4l80 is physically bigger, bell housing is bigger and it's longer over all by like an inch or so, and heavier. The 4l60e also has a 27 spline output shaft and the 4l80 has a 32 spline. So you'll have to figure out how to mate it to the factory transfer case or go with an aftermarket transfer case.
I'm sure others will agree. If you're going this deep, just swap the 3.7 with a ls v8.
To mate a ls with the stock transmission youll need a new wiring harness. All of the accessory drive stuff, etc.
Remember the h3 is a pass drop front axle, so the transfer case is passenger drop. That makes is difficult to do complete drive train swaps.
Either have to do engine/trans/tcase and an sas to swap the front around. Or engine/w/stock trans and keep the front axle as is.
It just comes down to how many different puzzles do you want to solve